Enola™ Rare Disease Investigator

Enola RDI Image

Enola is a symptom checker for undiagnosed rare disease patients and their clinicians. It uses real-world evidence to create a prioritised differential diagnosis (DDx) based on the symptoms and findings of the patient. This helps to narrow-down and prioritise further investigation and testing and ensures statistically significant rare diseases are considered. Combined with real-world patient data and evidence, it has the potential to dramatically reduce the diagnostic odyssey faced by patients with an undiagnosed rare disease, currently between 5 and 7 years.

Take a look at Enola but please remember this is only a demonstration of technical feasability (Proof of Concept) and not a medical device. It is not a sympton checker and it does not include common diseases. It should not be used as a substitute for medical advice from a physician.

Undiagnosed and rare diseases are a huge challenge for healthcare systems and patients. For more on the scale of the problem, initiatives to improve diagnosis and treatments and training opportunities see:

  1. Rare X – a collaborative platform for global data sharing and analysis to accelerate treatments for rare disease.
  2. UDNF aims to foster collaboration among patients, clinicians, and scientists to enhance the quality of life of undiagnosed and ultra-rare disease patients.
  3. EURODIS Open Academy aims to provide training that empowers not only its member organisations and volunteers, but anyone interested in learning more about the rare disease landscape.
  4. England Rare Disease action Plan – In this first England Rare Diseases Action Plan, we report on progress made, and take a significant step forward in transforming the collective priorities of the UK Rare Diseases Framework into tangible and concrete action.
  5. Orphanet maintains the Orphanet nomenclature of rare diseases, essential in improving the visibility of rare diseases in health and research information systems: each disease in Orphanet is attributed a unique and stable identifier, the ORPHAcode.